| Product Name | Benzene sulfonamide ( BSA ) |
| Synonyms: | Benzenesulphonamide; Benzene Sulfonamide; Benzosuifqnamide; Benzene sulfonamtde |
| CAS NO. | 98-10-2 |
| Molecular formula | C6H7NO2S |
| Molecular structure |
|
| Packing | 25kg woven bag |
| Product usage | It's as intermediates for organic synthesis, pharmaceutical, plasticizer, dye intermediates, fluorescence resin. |
| REACH Registration | Yes |
| Class or division | Dangerous GoodsUN NumberPacking GroupG/C---- |
| H.S.CODE | 2935009090 |
| Contact | Jessica Xuan |
Benzene sulfonamide ( BSA ) COA（Certificate of Analysis）
| CHECK POINT | UNIT | SPECIFICATIONS |
| Appearance | -- | White Crystalline Powder |
| Purity | % min | 99 |
| Melting Point | °C min | 152 |
| Water | % max | 0.3 |
| Colority(APHA) | Pt/Co max | 50 |
| Chloride | ppm max | 100 |
| Free Acid | % max | 0.2 |
| Diphenyl Sulfone | % max | 0.3 |
Benzene sulfonamide ( BSA )
according to Regulation (EC) No. 1907/2006
Version 6.3
Revision Date 22.09.2025
1.1 Product identifiers
Product name: Benzenesulfonamide
Product Number: 108146
Brand: Aldrich
REACH No.: A registration number is not available for this substance as the substance or its uses are exempted from registration or the annual tonnage does not require a registration.
CAS-No.: 98-10-2
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses: Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company: Sigma-Aldrich (Shanghai) Trading Co.Ltd.
509 Renqing Road
Zhangjiang High Tech East Park, Pudong
SHANGHAI 201201 SHANGHAI CHINA
Telephone: +86 21 6141-5566
Fax: +86 21 6141-5567
1.4 Emergency telephone number
Emergency Phone #: +86 532 83889090 (NRCC) 400 120 4937 (CHEMTREC)
2.1 Classification of the substance or mixture
Acute toxicity, (Category 4)
H302: Harmful if swallowed.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Signal Word: Warning
Hazard Statements: H302 Harmful if swallowed.
Precautionary Statements: none
Supplemental Hazard Statements: none
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
3.1 Substances
Formula: C6H7NO2S
Molecular weight: 157.19 g/mol
CAS-No.: 98-10-2
EC-No.: 202-637-1
Component
Benzenesulphonamide
CAS-No.: 98-10-2
EC-No.: 202-637-1
Classification: Acute Tox. 4; H302
Concentration: <= 100%
For the full text of the H-Statements mentioned in this Section, see Section 16.
4.1 Description of first aid measures
General advice
Show this safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
5.1 Extinguishing media
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Nitrogen oxides (NOx)
Sulphur oxides
5.3 Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.
5.4 Further information
Suppress (knock down) gases/vapours/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Dry.
Storage class
Storage class (TRGS 510): 11: Combustible Solids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested: Dermatril® (KCL 740 / Aldrich Z677272, Size M)
Data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Body Protection
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type P2
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.
9.1 Information on basic physical and chemical properties
a) Physical state: solid
b) Color: No data available
c) Odor: No data available
d) Melting point/freezing point: Melting point/ range: 149 - 152 °C - lit.
e) Initial boiling point and boiling range: No data available
f) Flammability (solid, gas): No data available
g) Upper/lower flammability or explosive limits: No data available
h) Flash point: No data available
i) Autoignition temperature: No data available
j) Decomposition temperature: No data available
k) pH: No data available
l) Viscosity: Viscosity, kinematic: No data available; Viscosity, dynamic: No data available
m) Water solubility: No data available
n) Partition coefficient: n-octanol/water: No data available
o) Vapor pressure: No data available
p) Density: No data available; Relative density: No data available
q) Relative vapour density: No data available
r) Particle characteristics: No data available
s) Explosive properties: No data available
t) Oxidizing properties: No data available
9.2 Other safety information
No data available
10.1 Reactivity
No data available
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature).
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
no information available
10.5 Incompatible materials
Strong oxidizing agents, Strong bases
10.6 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 991 mg/kg
Remarks: (RTECS)
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Remarks: No data available
Serious eye damage/eye irritation
Remarks: No data available
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
No data available
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information
RTECS: DA9380000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
12.1 Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
13.1 Waste treatment methods
No data available
14.1 UN number
ADR/RID: -
IMDG: -
IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: -
IMDG: -
IATA: -
14.4 Packaging group
ADR/RID: -
IMDG: -
IATA: -
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA: no
14.6 Special precautions for user
No data available
Further information
Not classified as dangerous in the meaning of transport regulations.
14.7 Maritime transport in bulk according to IMO instruments
Not applicable for product as supplied.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment
For this product a chemical safety assessment was not carried out
Full text of H-Statements
H302: Harmful if swallowed.
Full text of other abbreviations
ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways; ADR - Agreement concerning the International Carriage of Dangerous Goods by Road; AIIC - Australian Inventory of Industrial Chemicals; ASTM - American Society for the Testing of Materials; bw - Body weight; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute for Standardisation; DSL - Domestic Substances List (Canada); ECx - Concentration associated with x% response; ELx - Loading rate associated with x% response; EmS - Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with x% growth rate response; GHS - Globally Harmonised System; GLP - Good Laboratory Practice; IARC - International Agency for Research on Cancer; IATA - International Air Transport Association; IBC - International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO - International Maritime Organisation; ISHL - Industrial Safety and Health Law (Japan); ISO - International Organisation for Standardisation; KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50% of a test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. - Not Otherwise Specified; NO(A)EC - No Observed (Adverse) Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading Rate; NZIoC - New Zealand Inventory of Chemicals; OECD - Organisation for Economic Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; RID - Regulations concerning the International Carriage of Dangerous Goods by Rail; SADT - Self-Accelerating Decomposition Temperature; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TECI - Thailand Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (United States); UN - United Nations; UNRTDG - United Nations Recommendations on the Transport of Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative
Further information
The information is believed to be correct but is not exhaustive and will be used solely as a guideline, which is based on current knowledge of the chemical substance or mixture and is applicable to appropriate safety precautions for the product. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.
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Product: Benzene sulfonamide
1. Product Identification
Product Name: Benzenesulfonamide
Synonyms: Benzene sulphonamide
CAS Number: 98-10-2
EINECS Number: 202-637-1
Chemical Formula: C6H7NO2S
Molecular Weight: 157.19 g/mol
2. Physical and Chemical Properties
Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: \(151 - 155 \, ^\circ\text{C}$ ($304 - 311 \, ^\circ\text{F}\))
Boiling Point: 379∘C (760 mmHg) (Decomposes)
Solubility:
Slightly soluble in water.
Soluble in ethanol, ether, acetone, and alkali solutions.
Density (Specific Gravity): Approx. 1.39 g/cm³
3. Typical Specifications
Assay (Purity): ≥98.5% (by HPLC or Titration)
Moisture Content: ≤0.5% (by Karl Fischer)
Appearance: Conforms to standard (White crystalline powder)
Melting Range: 151−155∘C
4. Applications
Pharmaceutical Intermediate: Used as a key intermediate in the synthesis of sulfa drugs (sulfonamide antibiotics).
Chemical Synthesis: Acts as a building block for various organic compounds, including dyes, herbicides, and photochemicals.
Plasticizer: Used in the manufacture of plasticizers for resins and polymers.
Research: Employed in biochemical research, notably as an inhibitor of carbonic anhydrase.
5. Storage and Handling
Storage: Store in a cool, dry, well-ventilated place. Keep container tightly closed and sealed until ready for use.
Handling: Avoid breathing dust. Use with adequate ventilation. Avoid contact with skin, eyes, and clothing.
6. Packaging
Typically available in 25 kg fiber drums or woven bags with plastic liners, or as specified by the customer.
Disclaimer: The information provided in this TDS is for reference purposes only and is based on typical data. It does not constitute a specification.
Benzene sulfonamide ( BSA )
